These data reinforce the notion that low tidal volumes should be used in these patients, especially when low lung compliance is measured.2 Michela Botta and colleagues described ventilator management in a large cohort of patients with COVID-19 on mechanical ventilation.1 Their study provides important data on ventilator settings in this population and shows that high tidal volumes on the first day of ventilation are associated with a higher risk of 28-day mortality.
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